Description
COMPOSITION:
Each capsule contains: Selpercatinib…..………… 40mg
INDICATION:
LuciSel is a kinase inhibitor indicated for the treatment of:
· Adult patients with metastatic RET fusion-positive non-small cell lung cancer (NSCLC).
· Adult and pediatric patients 12 years of age and older with advanced or metastatic RET-mutant medullary thyroid cancer (MTC) who require systemic therapy.
· Adult and pediatric patients 12 years of age and older with advanced or metastatic RET fusion-positive thyroid cancer who require systemic therapy and who are radioactive iodine-refractory (if radioactive iodine is appropriate)
DOSAGE AND USE:
Select patients for treatment with LuciSel based on the presence of a RET gene fusion (NSCLC or thyroid) or specific RET gene mutation (MTC).
Recommended dosage in adults and pediatric patients 12 years of age or older is based on weight:
·Less than 50 kg: 120 mg orally twice daily
·50 kg or greater: 160 mg orally twice daily
Reduce LuciSel dose in patients with severe hepatic impairment.
Capsule should be swallowed whole & not chewed or crushed.
STORAGE:
in a dry place and store at 20°C to 25°C.
MANUFACTURED AND MARKETED BY:
LUCIUS PHARMACEUTICALS(LAO) CO., LTD
No.26, Thongmang village, Xaythany district, Vientiane Capital, Laos
WARNING:
Keep medicine out of the reach of Children. Do not administered LuciSel in Pregnancy and Lactation patient treatment.
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